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Entinostat up-regulates the CAMP gene encoding LL-37 via activation of STAT3 and HIF-1α transcription factors

Bacterial resistance against classical antibiotics is a growing problem and the development of new antibiotics is limited. Thus, novel alternatives to antibiotics are warranted. Antimicrobial peptides (AMPs) are effector molecules of innate immunity that can be induced by several compounds, includin...

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Detalles Bibliográficos
Autores principales: Miraglia, Erica, Nylén, Frank, Johansson, Katarina, Arnér, Elias, Cebula, Marcus, Farmand, Susan, Ottosson, Håkan, Strömberg, Roger, Gudmundsson, Gudmundur H., Agerberth, Birgitta, Bergman, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025742/
https://www.ncbi.nlm.nih.gov/pubmed/27633343
http://dx.doi.org/10.1038/srep33274