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An integrative and comparative study of pan-cancer transcriptomes reveals distinct cancer common and specific signatures

To investigate the commonalities and specificities across tumor lineages, we perform a systematic pan-cancer transcriptomic study across 6744 specimens. We find six pan-cancer subnetwork signatures which relate to cell cycle, immune response, Sp1 regulation, collagen, muscle system and angiogenesis....

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Detalles Bibliográficos
Autores principales: Cao, Zhen, Zhang, Shihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025752/
https://www.ncbi.nlm.nih.gov/pubmed/27633916
http://dx.doi.org/10.1038/srep33398