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Integrated stress response of vertebrates is regulated by four eIF2α kinases

The integrated stress response (ISR) is a cytoprotective pathway initiated upon phosphorylation of the eukaryotic translation initiation factor 2 (eIF2α) residue designated serine-51, which is critical for translational control in response to various stress conditions. Four eIF2α kinases, namely hem...

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Detalles Bibliográficos
Autores principales: Taniuchi, Shusuke, Miyake, Masato, Tsugawa, Kazue, Oyadomari, Miho, Oyadomari, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025754/
https://www.ncbi.nlm.nih.gov/pubmed/27633668
http://dx.doi.org/10.1038/srep32886