Cargando…
Integrated stress response of vertebrates is regulated by four eIF2α kinases
The integrated stress response (ISR) is a cytoprotective pathway initiated upon phosphorylation of the eukaryotic translation initiation factor 2 (eIF2α) residue designated serine-51, which is critical for translational control in response to various stress conditions. Four eIF2α kinases, namely hem...
Autores principales: | Taniuchi, Shusuke, Miyake, Masato, Tsugawa, Kazue, Oyadomari, Miho, Oyadomari, Seiichi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025754/ https://www.ncbi.nlm.nih.gov/pubmed/27633668 http://dx.doi.org/10.1038/srep32886 |
Ejemplares similares
-
Nanosecond pulsed electric fields induce the integrated stress response via reactive oxygen species-mediated heme-regulated inhibitor (HRI) activation
por: Hamada, Yoshimasa, et al.
Publicado: (2020) -
Integrated stress response regulates GDF15 secretion from adipocytes, preferentially suppresses appetite for a high-fat diet and improves obesity
por: Miyake, Masato, et al.
Publicado: (2021) -
PERK-mediated translational control is required for collagen secretion in chondrocytes
por: Hisanaga, Satoshi, et al.
Publicado: (2018) -
Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity
por: Kitakaze, Keisuke, et al.
Publicado: (2019) -
Skeletal muscle–specific eukaryotic translation initiation factor 2α phosphorylation controls amino acid metabolism and fibroblast growth factor 21–mediated non–cell-autonomous energy metabolism
por: Miyake, Masato, et al.
Publicado: (2016)