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Structural basis underlying viral hijacking of a histone chaperone complex

The histone H3.3 chaperone DAXX is implicated in formation of heterochromatin and transcription silencing, especially for newly infecting DNA virus genomes entering the nucleus. Epstein-Barr virus (EBV) can efficiently establish stable latent infection as a chromatinized episome in the nucleus of in...

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Detalles Bibliográficos
Autores principales: Huang, Hongda, Deng, Zhong, Vladimirova, Olga, Wiedmer, Andreas, Lu, Fang, Lieberman, Paul M., Patel, Dinshaw J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025803/
https://www.ncbi.nlm.nih.gov/pubmed/27581705
http://dx.doi.org/10.1038/ncomms12707