Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells

High concentrations of glucose and palmitate increase endothelial cell inflammation and apoptosis, events that often precede atherogenesis. They may do so by decreasing basal autophagy and AMP-activated protein kinase (AMPK) activity, although the mechanisms by which this occurs are not clear. Decre...

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Detalles Bibliográficos
Autores principales: Weikel, Karen A., Cacicedo, José M., Ruderman, Neil B., Ido, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025810/
https://www.ncbi.nlm.nih.gov/pubmed/27534430
http://dx.doi.org/10.1042/BSR20160174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025810/
https://www.ncbi.nlm.nih.gov/pubmed/27534430
http://dx.doi.org/10.1042/BSR20160174

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