Cargando…

Redox-dependent Regulation of Gluconeogenesis by a Novel Mechanism Mediated by a Peroxidatic Cysteine of Peroxiredoxin

Peroxiredoxin is an abundant peroxidase, but its non-peroxidase function is also important. In this study, we discovered that Tsa1, a major peroxiredoxin of budding yeast cells, is required for the efficient flux of gluconeogenesis. We found that the suppression of pyruvate kinase (Pyk1) via the int...

Descripción completa

Detalles Bibliográficos
Autores principales: Irokawa, Hayato, Tachibana, Tsuyoshi, Watanabe, Toshihiko, Matsuyama, Yuka, Motohashi, Hozumi, Ogasawara, Ayako, Iwai, Kenta, Naganuma, Akira, Kuge, Shusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025857/
https://www.ncbi.nlm.nih.gov/pubmed/27634403
http://dx.doi.org/10.1038/srep33536

Ejemplares similares