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Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is caused by genetic deficiency of dystrophin and characterized by massive structural and functional changes of skeletal muscle tissue, leading to terminal muscle failure. We recently generated a novel genetically engineered pig model reflecting pathological hallmar...

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Detalles Bibliográficos
Autores principales: Fröhlich, Thomas, Kemter, Elisabeth, Flenkenthaler, Florian, Klymiuk, Nikolai, Otte, Kathrin A., Blutke, Andreas, Krause, Sabine, Walter, Maggie C., Wanke, Rüdiger, Wolf, Eckhard, Arnold, Georg J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025886/
https://www.ncbi.nlm.nih.gov/pubmed/27634466
http://dx.doi.org/10.1038/srep33362