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Synthetic Receptors for the High‐Affinity Recognition of O‐GlcNAc Derivatives

The combination of a pyrenyl tetraamine with an isophthaloyl spacer has led to two new water‐soluble carbohydrate receptors (“synthetic lectins”). Both systems show outstanding affinities for derivatives of N‐acetylglucosamine (GlcNAc) in aqueous solution. One receptor binds the methyl glycoside Glc...

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Detalles Bibliográficos
Autores principales: Rios, Pablo, Carter, Tom S., Mooibroek, Tiddo J., Crump, Matthew P., Lisbjerg, Micke, Pittelkow, Michael, Supekar, Nitin T., Boons, Geert‐Jan, Davis, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026062/
https://www.ncbi.nlm.nih.gov/pubmed/26822115
http://dx.doi.org/10.1002/anie.201510611