Mutational analysis of the Aspergillus ambient pH receptor PalH underscores its potential as a target for antifungal compounds

The pal/RIM ambient pH signalling pathway is crucial for the ability of pathogenic fungi to infect hosts. The Aspergillus nidulans 7‐TMD receptor PalH senses alkaline pH, subsequently facilitating ubiquitination of the arrestin PalF. Ubiquitinated PalF triggers downstream signalling events. The mech...

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Detalles Bibliográficos
Autores principales: Lucena‐Agell, Daniel, Hervás‐Aguilar, América, Múnera‐Huertas, Tatiana, Pougovkina, Olga, Rudnicka, Joanna, Galindo, Antonio, Tilburn, Joan, Arst, Herbert N., Peñalva, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026065/
https://www.ncbi.nlm.nih.gov/pubmed/27279148
http://dx.doi.org/10.1111/mmi.13438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026065/
https://www.ncbi.nlm.nih.gov/pubmed/27279148
http://dx.doi.org/10.1111/mmi.13438

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