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Shear-Induced Amyloid Formation in the Brain: I. Potential Vascular and Parenchymal Processes
Shear distortion of amyloid-beta (Aβ) solutions accelerates amyloid cascade reactions that may yield different toxic oligomers than those formed in quiescent solutions. Recent experiments indicate that cerebrospinal fluid (CSF) and interstitial fluid (ISF) containing Aβ flow through narrow brain per...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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IOS Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026135/ https://www.ncbi.nlm.nih.gov/pubmed/27567812 http://dx.doi.org/10.3233/JAD-160027 |