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Shear-Induced Amyloid Formation in the Brain: I. Potential Vascular and Parenchymal Processes

Shear distortion of amyloid-beta (Aβ) solutions accelerates amyloid cascade reactions that may yield different toxic oligomers than those formed in quiescent solutions. Recent experiments indicate that cerebrospinal fluid (CSF) and interstitial fluid (ISF) containing Aβ flow through narrow brain per...

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Detalles Bibliográficos
Autor principal:	Trumbore, Conrad N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2016
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026135/ https://www.ncbi.nlm.nih.gov/pubmed/27567812 http://dx.doi.org/10.3233/JAD-160027

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