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The CHEK2 del5395 is a founder mutation without direct effects for cancer risk in the latvian population

Our objective was to determine: 1) whether the checkpoint kinase 2 (CHEK2) del5395 (g.27417113-27422508 del, NC_000022.11) is a founder mutation in the Latvian population, 2) if there is an association between CHEK2 del5395 mutation and cancer risk, and 3) and whether the CHEK2 del5395 mutation impa...

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Detalles Bibliográficos
Autores principales: Plonis, J, Kalniete, D, Nakazawa-Miklasevica, M, Irmejs, A, Vjaters, E, Gardovskis, J, Miklasevics, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026266/
https://www.ncbi.nlm.nih.gov/pubmed/27785394
http://dx.doi.org/10.1515/bjmg-2015-0083