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Assessment of genotoxicity of vincristine, vinblastine and vinorelbine in human cultured lymphocytes: a comparative study

Vincristine (VCR), vinblastine (VBL) and vinorelbine (VRL) are anticancer agents from the Vinca alkaloid family that have the potential to induce genotoxic effect. The aim of the present study was to compare the genotoxic effect of VCR, VBL and VRL. Levels of 8-hydroxy-2-deoxy guanosine (8-OHdG) and...

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Detalles Bibliográficos
Autores principales: Mhaidat, NM, Alzoubi, KH, Khabour, OF, Alawneh, KZ, Raffee, LA, Alsatari, ES, Hussein, EI, Bani-Hani, KE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026275/
https://www.ncbi.nlm.nih.gov/pubmed/27785403
http://dx.doi.org/10.1515/bjmg-2016-0002