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The influence of CYP2C8*3 on carbamazepine serum concentration in epileptic pediatric patients

The aim of the present study was to investigate the distribution of CYP2C8 variants *3 and *5, as well as their effect on carbamazepine pharmacokinetic properties, in 40 epileptic pediatric patients on carbamazepine treatment. Genotyping was conducted using polymerase chain reaction-restriction frag...

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Detalles Bibliográficos
Autores principales: Milovanovic, DD, Milovanovic, JR, Radovanovic, M, Radosavljevic, I, Obradovic, S, Jankovic, S, Milovanovic, D, Djordjevic, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026276/
https://www.ncbi.nlm.nih.gov/pubmed/27785404
http://dx.doi.org/10.1515/bjmg-2016-0003