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The influence of CYP2C8*3 on carbamazepine serum concentration in epileptic pediatric patients
The aim of the present study was to investigate the distribution of CYP2C8 variants *3 and *5, as well as their effect on carbamazepine pharmacokinetic properties, in 40 epileptic pediatric patients on carbamazepine treatment. Genotyping was conducted using polymerase chain reaction-restriction frag...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
De Gruyter
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026276/ https://www.ncbi.nlm.nih.gov/pubmed/27785404 http://dx.doi.org/10.1515/bjmg-2016-0003 |