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SMCis: An Effective Algorithm for Discovery of Cis-Regulatory Modules
The discovery of cis-regulatory modules (CRMs) is a challenging problem in computational biology. Limited by the difficulty of using an HMM to model dependent features in transcriptional regulatory sequences (TRSs), the probabilistic modeling methods based on HMMs cannot accurately represent the dis...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026350/ https://www.ncbi.nlm.nih.gov/pubmed/27637070 http://dx.doi.org/10.1371/journal.pone.0162968 |