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SMCis: An Effective Algorithm for Discovery of Cis-Regulatory Modules

The discovery of cis-regulatory modules (CRMs) is a challenging problem in computational biology. Limited by the difficulty of using an HMM to model dependent features in transcriptional regulatory sequences (TRSs), the probabilistic modeling methods based on HMMs cannot accurately represent the dis...

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Detalles Bibliográficos
Autores principales: Guo, Haitao, Huo, Hongwei, Yu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026350/
https://www.ncbi.nlm.nih.gov/pubmed/27637070
http://dx.doi.org/10.1371/journal.pone.0162968