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Role of Chymase in the Development of Liver Cirrhosis and Its Complications: Experimental and Human Data

BACKGROUND: Tissue Angiotensin II (Ang-II), produced through local non ACE-dependent pathways, stimulates liver fibrogenesis, renal vasoconstriction and sodium retention. AIM: To highlight chymase-dependent pathway of Ang-II production in liver and kidney during cirrhosis development. METHODS: Liver...

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Detalles Bibliográficos
Autores principales: Sansoè, Giovanni, Aragno, Manuela, Mastrocola, Raffaella, Mengozzi, Giulio, Novo, Erica, Parola, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026361/
https://www.ncbi.nlm.nih.gov/pubmed/27637026
http://dx.doi.org/10.1371/journal.pone.0162644