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Replacing the PDZ-interacting C-termini of DSCAM and DSCAML1 with epitope tags causes different phenotypic severity in different cell populations

Different types of neurons in the retina are organized vertically into layers and horizontally in a mosaic pattern that helps ensure proper neural network formation and information processing throughout the visual field. The vertebrate Dscams (DSCAM and DSCAML1) are cell adhesion molecules that supp...

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Detalles Bibliográficos
Autores principales: Garrett, Andrew M, Tadenev, Abigail LD, Hammond, Yuna T, Fuerst, Peter G, Burgess, Robert W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026468/
https://www.ncbi.nlm.nih.gov/pubmed/27637097
http://dx.doi.org/10.7554/eLife.16144