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bMERB domains are bivalent Rab8 family effectors evolved by gene duplication

In their active GTP-bound form, Rab proteins interact with proteins termed effector molecules. In this study, we have thoroughly characterized a Rab effector domain that is present in proteins of the Mical and EHBP families, both known to act in endosomal trafficking. Within our study, we show that...

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Detalles Bibliográficos
Autores principales: Rai, Amrita, Oprisko, Anastasia, Campos, Jeremy, Fu, Yangxue, Friese, Timon, Itzen, Aymelt, Goody, Roger S, Gazdag, Emerich Mihai, Müller, Matthias P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026484/
https://www.ncbi.nlm.nih.gov/pubmed/27552051
http://dx.doi.org/10.7554/eLife.18675