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Identification of Interferon-Stimulated Genes with Antiretroviral Activity

Interferons (IFNs) exert their anti-viral effects by inducing the expression of hundreds of IFN-stimulated genes (ISGs). The activity of known ISGs is insufficient to account for the antiretroviral effects of IFN, suggesting that ISGs with antiretroviral activity are yet to be described. We construc...

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Detalles Bibliográficos
Autores principales: Kane, Melissa, Zang, Trinity M., Rihn, Suzannah J., Zhang, Fengwen, Kueck, Tonya, Alim, Mudathir, Schoggins, John, Rice, Charles M., Wilson, Sam J., Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026698/
https://www.ncbi.nlm.nih.gov/pubmed/27631702
http://dx.doi.org/10.1016/j.chom.2016.08.005