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Signal Integration by the IκB Protein Pickle Shapes Drosophila Innate Host Defense
Pattern recognition receptors are activated following infection and trigger transcriptional programs important for host defense. Tight regulation of NF-κB activation is critical to avoid detrimental and misbalanced responses. We describe Pickle, a Drosophila nuclear IκB that integrates signaling inp...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026699/ https://www.ncbi.nlm.nih.gov/pubmed/27631699 http://dx.doi.org/10.1016/j.chom.2016.08.003 |