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Identification and Potential Regulatory Properties of Evolutionary Conserved Regions (ECRs) at the Schizophrenia-Associated MIR137 Locus

Genome-wide association studies (GWAS) have identified a region at chromosome 1p21.3, containing the microRNA MIR137, to be among the most significant associations for schizophrenia. However, the mechanism by which genetic variation at this locus increases risk of schizophrenia is unknown. Identifyi...

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Detalles Bibliográficos
Autores principales: Gianfrancesco, Olympia, Griffiths, Daniel, Myers, Paul, Collier, David A., Bubb, Vivien J., Quinn, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026716/
https://www.ncbi.nlm.nih.gov/pubmed/27525637
http://dx.doi.org/10.1007/s12031-016-0812-x