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Initiation of antiretroviral therapy before detection of colonic infiltration by HIV reduces viral reservoirs, inflammation and immune activation

INTRODUCTION: Colonic infiltration by HIV occurs soon after infection, establishing a persistent viral reservoir and a barrier to cure. We investigated virologic and immunologic correlates of detectable colonic HIV RNA during acute HIV infection (AHI) and their response to antiretroviral treatment (...

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Detalles Bibliográficos
Autores principales: Crowell, Trevor A, Fletcher, James LK, Sereti, Irini, Pinyakorn, Suteeraporn, Dewar, Robin, Krebs, Shelly J, Chomchey, Nitiya, Rerknimitr, Rungsun, Schuetz, Alexandra, Michael, Nelson L, Phanuphak, Nittaya, Chomont, Nicolas, Ananworanich, Jintanat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026729/
https://www.ncbi.nlm.nih.gov/pubmed/27637172
http://dx.doi.org/10.7448/IAS.19.1.21163