General continuous-time Markov model of sequence evolution via insertions/deletions: are alignment probabilities factorable?

BACKGROUND: Insertions and deletions (indels) account for more nucleotide differences between two related DNA sequences than substitutions do, and thus it is imperative to develop a stochastic evolutionary model that enables us to reliably calculate the probability of the sequence evolution through...

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Detalles Bibliográficos
Autor principal: Ezawa, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026781/
https://www.ncbi.nlm.nih.gov/pubmed/27638547
http://dx.doi.org/10.1186/s12859-016-1105-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026781/
https://www.ncbi.nlm.nih.gov/pubmed/27638547
http://dx.doi.org/10.1186/s12859-016-1105-7

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