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General continuous-time Markov model of sequence evolution via insertions/deletions: are alignment probabilities factorable?
BACKGROUND: Insertions and deletions (indels) account for more nucleotide differences between two related DNA sequences than substitutions do, and thus it is imperative to develop a stochastic evolutionary model that enables us to reliably calculate the probability of the sequence evolution through...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026781/ https://www.ncbi.nlm.nih.gov/pubmed/27638547 http://dx.doi.org/10.1186/s12859-016-1105-7 |