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NPR3 protects cardiomyocytes from apoptosis through inhibition of cytosolic BRCA1 and TNF-α

Natriuretic peptide receptor 3 (NPR3) is a clearance receptor by binding and internalizing natriuretic peptides (NPs) for ultimate degradation. Patients with cardiac failure show elevated NPs. NPs are linked to poor long-term survival because of their apoptotic effects. However, the underling mechan...

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Detalles Bibliográficos
Autores principales: Lin, Dong, Chai, Yubo, Izadpanah, Reza, Braun, Stephen E., Alt, Eckhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026813/
https://www.ncbi.nlm.nih.gov/pubmed/27494651
http://dx.doi.org/10.1080/15384101.2016.1148843