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Targeted next-generation sequencing of TP53 in oral tongue carcinoma from non-smokers
BACKGROUND: Little is known regarding the etiology and genomic underpinnings of Oral Tongue Squamous Cell Carcinoma (OTSCC) in patients who lack traditional risk factors, yet the incidence is increasing. In particular, the rate, and role, of TP53 mutations in this cohort has been heavily debated in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027093/ https://www.ncbi.nlm.nih.gov/pubmed/27640185 http://dx.doi.org/10.1186/s40463-016-0160-4 |