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Regulatory T Cells Are Dispensable for Tolerance to RBC Antigens

Autoimmune hemolytic anemia (AIHA) occurs when pathogenic autoantibodies against red blood cell (RBC) antigens are generated. While the basic disease pathology of AIHA is well studied, the underlying mechanism(s) behind the failure in tolerance to RBC autoantigens are poorly understood. Thus, to inv...

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Detalles Bibliográficos
Autores principales: Richards, Amanda L., Kapp, Linda M., Wang, Xiaohong, Howie, Heather L., Hudson, Krystalyn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027202/
https://www.ncbi.nlm.nih.gov/pubmed/27698653
http://dx.doi.org/10.3389/fimmu.2016.00348