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Novel Function of Sprouty4 as a Regulator of Stemness and Differentiation of Embryonic Stem Cells

Sprouty (Spry) genes encode inhibitors of the receptor tyrosine kinase signaling cascade, which plays important roles in stem cells. However, the role of Spry4 in the stemness of embryonic stem cells has not been fully elucidated. Here, we used mouse embryonic stem cells (mESCs) as a model system to...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Young, Park, Sunghyun, Kim, Kwang-Soo, Ko, Jeong-Jae, Lee, Soohong, Kim, Keun Pil, Park, Kyung-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Developmental Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027223/
https://www.ncbi.nlm.nih.gov/pubmed/27660833
http://dx.doi.org/10.12717/DR.2016.20.2.171