PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development

Adrenal cortex physiology relies on functional zonation, essential for production of aldosterone by outer zona glomerulosa (ZG) and glucocorticoids by inner zona fasciculata (ZF). The cortex undergoes constant cell renewal, involving recruitment of subcapsular progenitors to ZG fate and subsequent l...

Descripción completa

Detalles Bibliográficos
Autores principales: Drelon, Coralie, Berthon, Annabel, Sahut-Barnola, Isabelle, Mathieu, Mickaël, Dumontet, Typhanie, Rodriguez, Stéphanie, Batisse-Lignier, Marie, Tabbal, Houda, Tauveron, Igor, Lefrançois-Martinez, Anne-Marie, Pointud, Jean-Christophe, Gomez-Sanchez, Celso E., Vainio, Seppo, Shan, Jingdong, Sacco, Sonia, Schedl, Andreas, Stratakis, Constantine A., Martinez, Antoine, Val, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027289/
https://www.ncbi.nlm.nih.gov/pubmed/27624192
http://dx.doi.org/10.1038/ncomms12751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027289/
https://www.ncbi.nlm.nih.gov/pubmed/27624192
http://dx.doi.org/10.1038/ncomms12751

Ejemplares similares