Soluble Receptor for Advanced Glycation End Product Ameliorates Chronic Intermittent Hypoxia Induced Renal Injury, Inflammation, and Apoptosis via P38/JNK Signaling Pathways

Obstructive sleep apnea (OSA) associated chronic kidney disease is mainly caused by chronic intermittent hypoxia (CIH) triggered tissue damage. Receptor for advanced glycation end product (RAGE) and its ligand high mobility group box 1 (HMGB1) are expressed on renal cells and mediate inflammatory re...

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Detalles Bibliográficos
Autores principales: Wu, Xu, Gu, Wenyu, Lu, Huan, Liu, Chengying, Yu, Biyun, Xu, Hui, Tang, Yaodong, Li, Shanqun, Zhou, Jian, Shao, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027322/
https://www.ncbi.nlm.nih.gov/pubmed/27688824
http://dx.doi.org/10.1155/2016/1015390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027322/
https://www.ncbi.nlm.nih.gov/pubmed/27688824
http://dx.doi.org/10.1155/2016/1015390

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