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Estrogen receptor alpha activation enhances mitochondrial function and systemic metabolism in high‐fat‐fed ovariectomized mice

Estrogen impacts insulin action and cardiac metabolism, and menopause dramatically increases cardiometabolic risk in women. However, the mechanism(s) of cardiometabolic protection by estrogen remain incompletely understood. Here, we tested the effects of selective activation of E2 receptor alpha (ER...

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Detalles Bibliográficos
Autores principales: Hamilton, Dale J., Minze, Laurie J., Kumar, Tanvi, Cao, Tram N., Lyon, Christopher J., Geiger, Paige C., Hsueh, Willa A., Gupte, Anisha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027347/
https://www.ncbi.nlm.nih.gov/pubmed/27582063
http://dx.doi.org/10.14814/phy2.12913