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Increased pulmonary arteriolar tone associated with lung oxidative stress and nitric oxide in a mouse model of Alzheimer's disease

Vascular dysfunction and decreased cerebral blood flow are linked to Alzheimer's disease (AD). Loss of endothelial nitric oxide (NO) and oxidative stress in human cerebrovascular endothelium increase expression of amyloid precursor protein (APP) and enhance production of the Aβ peptide, suggest...

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Detalles Bibliográficos
Autores principales: Roberts, Andrew M., Jagadapillai, Rekha, Vaishnav, Radhika A., Friedland, Robert P., Drinovac, Robert, Lin, Xingyu, Gozal, Evelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027359/
https://www.ncbi.nlm.nih.gov/pubmed/27604401
http://dx.doi.org/10.14814/phy2.12953