Increased hemoglobin–oxygen affinity ameliorates bleomycin‐induced hypoxemia and pulmonary fibrosis

Although exertional dyspnea and worsening hypoxia are hallmark clinical features of idiopathic pulmonary fibrosis (IPF), no drug currently available could treat them. GBT1118 is a novel orally bioavailable small molecule that binds to hemoglobin and produces a concentration‐dependent left shift of t...

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Detalles Bibliográficos
Autores principales: Geng, Xin, Dufu, Kobina, Hutchaleelaha, Athiwat, Xu, Qing, Li, Zhe, Li, Chien‐Ming, Patel, Mira P., Vlahakis, Nicholas, Lehrer‐Graiwer, Josh, Oksenberg, Donna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027366/
https://www.ncbi.nlm.nih.gov/pubmed/27624688
http://dx.doi.org/10.14814/phy2.12965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027366/
https://www.ncbi.nlm.nih.gov/pubmed/27624688
http://dx.doi.org/10.14814/phy2.12965

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