Synergistic activation of Arg1 gene by retinoic acid and IL-4 involves chromatin remodeling for transcription initiation and elongation coupling

All-trans Retinoic acid (RA) and its derivatives are potent therapeutics for immunological functions including wound repair. However, the molecular mechanism of RA modulation in innate immunity is poorly understood, especially in macrophages. We found that topical application of RA significantly imp...

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Detalles Bibliográficos
Autores principales: Lee, Bomi, Wu, Cheng-Ying, Lin, Yi-Wei, Park, Sung Wook, Wei, Li-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027474/
https://www.ncbi.nlm.nih.gov/pubmed/27166374
http://dx.doi.org/10.1093/nar/gkw392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027474/
https://www.ncbi.nlm.nih.gov/pubmed/27166374
http://dx.doi.org/10.1093/nar/gkw392

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