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The SNF2 family ATPase LSH promotes cell-autonomous de novo DNA methylation in somatic cells

Methylation of DNA at carbon 5 of cytosine is essential for mammalian development and implicated in transcriptional repression of genes and transposons. New patterns of DNA methylation characteristic of lineage-committed cells are established at the exit from pluripotency by de novo DNA methyltransf...

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Detalles Bibliográficos
Autores principales: Termanis, Ausma, Torrea, Natalia, Culley, Jayne, Kerr, Alastair, Ramsahoye, Bernard, Stancheva, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027476/
https://www.ncbi.nlm.nih.gov/pubmed/27179028
http://dx.doi.org/10.1093/nar/gkw424