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The SNF2 family ATPase LSH promotes cell-autonomous de novo DNA methylation in somatic cells
Methylation of DNA at carbon 5 of cytosine is essential for mammalian development and implicated in transcriptional repression of genes and transposons. New patterns of DNA methylation characteristic of lineage-committed cells are established at the exit from pluripotency by de novo DNA methyltransf...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027476/ https://www.ncbi.nlm.nih.gov/pubmed/27179028 http://dx.doi.org/10.1093/nar/gkw424 |