An epigenetic switch regulates de novo DNA methylation at a subset of pluripotency gene enhancers during embryonic stem cell differentiation

Coordinated regulation of gene expression that involves activation of lineage specific genes and repression of pluripotency genes drives differentiation of embryonic stem cells (ESC). For complete repression of pluripotency genes during ESC differentiation, chromatin at their enhancers is silenced b...

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Detalles Bibliográficos
Autores principales: Petell, Christopher J., Alabdi, Lama, He, Ming, San Miguel, Phillip, Rose, Richard, Gowher, Humaira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027477/
https://www.ncbi.nlm.nih.gov/pubmed/27179026
http://dx.doi.org/10.1093/nar/gkw426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027477/
https://www.ncbi.nlm.nih.gov/pubmed/27179026
http://dx.doi.org/10.1093/nar/gkw426

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