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EZH2 is required for mouse oocyte meiotic maturation by interacting with and stabilizing spindle assembly checkpoint protein BubRI

Enhancer of zeste homolog 2 (EZH2) trimethylates histone H3 Lys 27 and plays key roles in a variety of biological processes. Stability of spindle assembly checkpoint protein BubR1 is essential for mitosis in somatic cells and for meiosis in oocytes. However, the role of EZH2 in oocyte meiotic matura...

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Detalles Bibliográficos
Autores principales: Qu, Yi, Lu, Danyu, Jiang, Hao, Chi, Xiaochun, Zhang, Hongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027481/
https://www.ncbi.nlm.nih.gov/pubmed/27226494
http://dx.doi.org/10.1093/nar/gkw463