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The catalytic efficiency of yeast ribonuclease III depends on substrate specific product release rate

Members of the ribonuclease III (RNase III) family regulate gene expression by triggering the degradation of double stranded RNA (dsRNA). Hundreds of RNase III cleavage targets have been identified and their impact on RNA maturation and stability is now established. However, the mechanism defining s...

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Detalles Bibliográficos
Autores principales: Comeau, Marc-Andre, Lafontaine, Daniel A., Abou Elela, Sherif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027489/
https://www.ncbi.nlm.nih.gov/pubmed/27257067
http://dx.doi.org/10.1093/nar/gkw507