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Boiler: lossy compression of RNA-seq alignments using coverage vectors

We describe Boiler, a new software tool for compressing and querying large collections of RNA-seq alignments. Boiler discards most per-read data, keeping only a genomic coverage vector plus a few empirical distributions summarizing the alignments. Since most per-read data is discarded, storage footp...

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Detalles Bibliográficos
Autores principales: Pritt, Jacob, Langmead, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027496/
https://www.ncbi.nlm.nih.gov/pubmed/27298258
http://dx.doi.org/10.1093/nar/gkw540