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Boiler: lossy compression of RNA-seq alignments using coverage vectors
We describe Boiler, a new software tool for compressing and querying large collections of RNA-seq alignments. Boiler discards most per-read data, keeping only a genomic coverage vector plus a few empirical distributions summarizing the alignments. Since most per-read data is discarded, storage footp...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027496/ https://www.ncbi.nlm.nih.gov/pubmed/27298258 http://dx.doi.org/10.1093/nar/gkw540 |