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NEpiC: a network-assisted algorithm for epigenetic studies using mean and variance combined signals

DNA methylation plays an important role in many biological processes. Existing epigenome-wide association studies (EWAS) have successfully identified aberrantly methylated genes in many diseases and disorders with most studies focusing on analysing methylation sites one at a time. Incorporating prio...

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Detalles Bibliográficos
Autores principales: Ruan, Peifeng, Shen, Jing, Santella, Regina M., Zhou, Shuigeng, Wang, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027497/
https://www.ncbi.nlm.nih.gov/pubmed/27302130
http://dx.doi.org/10.1093/nar/gkw546