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Mechanism of endonuclease cleavage by the HigB toxin

Bacteria encode multiple type II toxin–antitoxin modules that cleave ribosome-bound mRNAs in response to stress. All ribosome-dependent toxin family members structurally characterized to date adopt similar microbial RNase architectures despite possessing low sequence identities. Therefore, determini...

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Detalles Bibliográficos
Autores principales: Schureck, Marc A., Repack, Adrienne, Miles, Stacey J., Marquez, Jhomar, Dunham, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027501/
https://www.ncbi.nlm.nih.gov/pubmed/27378776
http://dx.doi.org/10.1093/nar/gkw598