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An AT-barrier mechanically controls DNA reannealing under tension

Regulation of genomic activity occurs through the manipulation of DNA by competent mechanoenzymes. Force-clamp optical tweezers that allow the structural dynamics of the DNA molecule to be measured were used here to investigate the kinetics of mechanically-driven strand reannealing. When the force o...

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Detalles Bibliográficos
Autores principales: Bongini, L., Pongor, C., Falorsi, G., Pertici, I., Kellermayer, M., Lombardi, V., Bianco, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027502/
https://www.ncbi.nlm.nih.gov/pubmed/27378772
http://dx.doi.org/10.1093/nar/gkw604