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An AT-barrier mechanically controls DNA reannealing under tension
Regulation of genomic activity occurs through the manipulation of DNA by competent mechanoenzymes. Force-clamp optical tweezers that allow the structural dynamics of the DNA molecule to be measured were used here to investigate the kinetics of mechanically-driven strand reannealing. When the force o...
Autores principales: | Bongini, L., Pongor, C., Falorsi, G., Pertici, I., Kellermayer, M., Lombardi, V., Bianco, P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027502/ https://www.ncbi.nlm.nih.gov/pubmed/27378772 http://dx.doi.org/10.1093/nar/gkw604 |
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