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Transient receptor potential channel 1/4 reduces subarachnoid hemorrhage-induced early brain injury in rats via calcineurin-mediated NMDAR and NFAT dephosphorylation

Transient receptor potential channel 1/4 (TRPC1/4) are considered to be related to subarachnoid hemorrhage (SAH)-induced cerebral vasospasm. In this study, a SAH rat model was employed to study the roles of TRPC1/4 in the early brain injury (EBI) after SAH. Primary cultured hippocampal neurons were...

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Detalles Bibliográficos
Autores principales: Wang, Zhong, Wang, Yibin, Tian, Xiaodi, Shen, Haitao, Dou, Yang, Li, Haiying, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027540/
https://www.ncbi.nlm.nih.gov/pubmed/27641617
http://dx.doi.org/10.1038/srep33577