Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism

Therapeutics aimed at blocking the cannabinoid 1 (CB1) receptor for treatment of obesity resulted in significant improvements in liver function, glucose uptake and pancreatic β-cell function independent of weight loss or CB1 receptor blockade in the brain, suggesting that peripherally-acting only CB...

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Detalles Bibliográficos
Autores principales: González-Mariscal, Isabel, Krzysik-Walker, Susan M., Doyle, Máire E., Liu, Qing-Rong, Cimbro, Raffaello, Santa-Cruz Calvo, Sara, Ghosh, Soumita, Cieśla, Łukasz, Moaddel, Ruin, Carlson, Olga D., Witek, Rafal P., O’Connell, Jennifer F., Egan, Josephine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027555/
https://www.ncbi.nlm.nih.gov/pubmed/27641999
http://dx.doi.org/10.1038/srep33302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027555/
https://www.ncbi.nlm.nih.gov/pubmed/27641999
http://dx.doi.org/10.1038/srep33302

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