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Single-Molecule Imaging Reveals the Activation Dynamics of Intracellular Protein Smad3 on Cell Membrane
Smad3 is an intracellular protein that plays a key role in propagating transforming growth factor β (TGF-β) signals from cell membrane to nucleus. However whether the transient process of Smad3 activation occurs on cell membrane and how it is regulated remains elusive. Using advanced live-cell singl...
Autores principales: | Li, Nan, Yang, Yong, He, Kangmin, Zhang, Fayun, Zhao, Libo, Zhou, Wei, Yuan, Jinghe, Liang, Wei, Fang, Xiaohong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027577/ https://www.ncbi.nlm.nih.gov/pubmed/27641076 http://dx.doi.org/10.1038/srep33469 |
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