Quantitative and combinatory determination of in situ phosphorylation of tau and its FTDP-17 mutants

Tau is hyperphosphorylated in the brains of patients with tauopathies, such as Alzheimer’s disease and frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). However, neither the mechanism of hyperphosphorylation nor its contribution to pathogenesis is known. We applied Phos-tag...

Descripción completa

Detalles Bibliográficos
Autores principales: Kimura, Taeko, Hosokawa, Tomohisa, Taoka, Masato, Tsutsumi, Koji, Ando, Kanae, Ishiguro, Koichi, Hosokawa, Masato, Hasegawa, Masato, Hisanaga, Shin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027580/
https://www.ncbi.nlm.nih.gov/pubmed/27641626
http://dx.doi.org/10.1038/srep33479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027580/
https://www.ncbi.nlm.nih.gov/pubmed/27641626
http://dx.doi.org/10.1038/srep33479

Ejemplares similares